{"id":3999,"date":"2020-03-18T18:11:04","date_gmt":"2020-03-18T18:11:04","guid":{"rendered":"https:\/\/www.sicklecelldisease.org\/?p=3999"},"modified":"2020-03-18T18:11:04","modified_gmt":"2020-03-18T18:11:04","slug":"sickle-cell-disease-and-covid-19-provider-directory","status":"publish","type":"post","link":"https:\/\/www.sicklecelldisease.org\/2020\/03\/18\/sickle-cell-disease-and-covid-19-provider-directory\/","title":{"rendered":"NEW &#8211; Sickle Cell Disease and COVID-19: Provider Advisory"},"content":{"rendered":"<p><strong><a href=\"https:\/\/www.sicklecelldisease.org\/wp-content\/uploads\/2020\/03\/5.27.20-MARAC-SCDAA-PROVIDER-ADVISORY-5-27-2020-2.pdf\">Download Provider Advisory<\/a><\/strong><br \/>\n<strong><a href=\"https:\/\/www.sicklecelldisease.org\/wp-content\/uploads\/2020\/03\/MARAC-SCDAA-Provider-Advisory-AFRO-4-1-2020.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Download Sub-Saharan African Provider Advisory<\/a><\/strong><\/p>\n<h2><strong>An Outline to Decrease Burden and Minimize Morbidity<\/strong><\/h2>\n<p><strong><em>This document will be updated as data and evidence emerge.<\/em><\/strong><br \/>\n<strong>May 27, 2020 <\/strong>&#8211; Sickle cell disease (SCD) affects 100,000 individuals in the United States and millions globally. Individuals living with SCD suffer from both acute and chronic complications that require close contact with the medical system. These include acute sickle cell pain, fever, and the acute chest syndrome (ACS) which is the term used for a constellation of findings that includes chest pain, cough, fever, hypoxia and new lung infiltrates. There is a significant concern that the overlap of lung disease from COVID-19 with ACS may result in increased complications and amplification of healthcare utilization among individuals with SCD. Moreover, individuals with SCD, in general, experience high utilization of acute care services including emergency departments and hospitals and often present with fever, signs and symptoms of pneumonia or evolving ACS, as well as acute sickle cell pain requiring parenteral therapy. Thus, there may be specific diagnostic, treatment and logistical challenges in meeting the healthcare needs of this population during the COVID-19 pandemic.<br \/>\nHere, we provide suggested guidelines for the acute and chronic disease management of patients with SCD given the multidimensional and evolving changes and challenges in our healthcare operational landscape.<\/p>\n<ul>\n<li>If possible, convert all routine in-person appointments to virtual or telephonic <strong>Do not simply cancel appointments as patients need guidance and planning now more than ever.<\/strong><\/li>\n<li>Educate patients and parents over the telephone about COVID-19 signs and symptoms and the importance of <strong>physical distancing<\/strong> to limit chances of exposure and infection. <strong>Encourage enhanced emotional connection through virtual or cellular-based modalities.<\/strong><\/li>\n<li>Counsel patients and parents to continue to seek medical help for fever and other signs of infection. Counsel them to <strong>call first<\/strong> &#8211; their hospital, doctor, or nurse &#8211; for advice on where to go safely for evaluation.<\/li>\n<li>Make sure patients have a thermometer and know how to use it and clean it after each use.<\/li>\n<li>Make certain your patients have an ample supply of all prescribed medication at home (including analgesics) to manage both acute and chronic pain. If needed, reach out to your state medical board to institute a waiver on duration of opioid.<\/li>\n<li>Prioritize the use of pharmacies who deliver medications to patients.<\/li>\n<li><strong>Counsel patients to adhere closely to use of hydroxyurea and other chronic medications such as L-glutamine, Voxelotor and Crizanlizumab as prescribed.<\/strong><\/li>\n<li>Consider starting and\/or optimizing existing therapies known to reduce sickle cell pain frequency (Hydroxyurea, L-glutamine, Crizanlizumab) as this is what most commonly brings older children and adults in direct contact with emergency departments and hospitals. The goal is to reduce this contact, if possible, to limit exposure to COVID-19.<\/li>\n<li>Halt all new subject enrollments for research requiring patient visits unless it is deemed in the patient\u2019s best interest or involves COVID-19 clinical investigation or compassionate use protocols for very ill patients.<\/li>\n<li>Encourage patients without fever or signs of infection to manage pain at home with oral medications to reduce hospitalizations and visits to the emergency department.<\/li>\n<li>Consider prescribing naloxone for home use and educating patients and parents on when and how to use it.<\/li>\n<li>Call in or e-prescribe analgesic medications to the patient\u2019s pharmacy and preferentially use pharmacies that deliver medications to patients\u2019 homes.<\/li>\n<li>Call patient frequently to assess response to home-based treatment and offer in-person evaluation if this fails. <strong>Note that some patients with SCD present initially with acute sickle cell pain therefore close telephone contact should be employed with low threshold for in-person evaluation and COVID-19 testing.<\/strong><\/li>\n<li>Urge patients to continue strict adherence to agents that reduce acute sickle cell pain frequency (e.g. Hydroxyurea, L-glutamine, Crizanlizumab) to reduce the likelihood of another pain episode.<\/li>\n<\/ul>\n<p>We recognize that almost all institutions have established COVID-19 task forces with specific protocols. We underscore that it is essential that every institution includes SCD patients as a high-risk category, thus we advise taking the following into consideration:<\/p>\n<ul>\n<li>Make every effort to interview the patient by telephone, text monitoring system, or video Temperature monitoring could be reported by phone or shown to a provider via video conferencing.<\/li>\n<li>For patients with COVID-19 symptoms (fever, cough, or shortness of breath):<\/li>\n<li>Schedule patient for an outpatient visit immediately. Avoid the emergency department (ED), if possible. If the ED must be used, call ahead to facilitate care and isolation.<\/li>\n<li>If it is possible at your center, test patient for COVID-19. If it is not possible, follow guidelines and collect appropriate sample and send to a testing facility.<\/li>\n<li>Follow standard of care for managing SCD and fever including culturing of blood and other specimen (as indicated), testing for typical viral infections, administration of empiric broad-spectrum antibiotics to cover encapsulated organisms (e.g. ceftriaxone), and assessing for signs of acute chest syndrome.<\/li>\n<li>If the patient is COVID-19 negative and close telephone contact is possible to assess routinely for progression of symptoms, consider management at home with oral<\/li>\n<li>If possible, give the patient an incentive spirometer to use at home.<\/li>\n<\/ul>\n<p>&nbsp;<br \/>\nThis is a rapidly evolving area of medicine without fully established standard of care for any population of patients, thus we advise taking the following into consideration when treating SCD patients with COVID-19:<\/p>\n<ul>\n<li><strong>Monitor closely for signs of ACS and treat aggressively<\/strong>.<\/li>\n<li>Be vigilant for signs of rapidly progressive ACS, especially in adults: thrombocytopenia, acute kidney injury, hepatic dysfunction, altered mental status, and multi-organ failure (Chaturvedi et al. Am J Hematol. 2016). Use standard treatment protocols for ACS.<\/li>\n<li>Standard of care for ACS includes empiric antibiotics and use of oseltamivir until influenza is ruled out, supplemental oxygen, incentive spirometry, and good pain control to reduce atelectasis.<\/li>\n<li>Transfusion for ACS \u2013 Transfusion should be performed in patients with worsening anemia, evidence of hypoxia and chest x-ray changes. Initiate simple transfusion if patient is symptomatic or there is significant anemia (hemoglobin &lt; 9 g\/dl or greater than a 2 g\/dl fall in hemoglobin; modified from NIH Recommendations). Initiate exchange transfusion for progression of hypoxia or clinical deterioration.<\/li>\n<li>Be vigilant for signs of Fat Emboli Syndrome: worsening anemia and mental status, hemolysis, thrombocytopenia, hypoalbuminemia, respiratory distress, and petechial rash. Can progress rapidly and mortality can be &gt;60% in 48hrs.<\/li>\n<li>SCD patients often have undiagnosed pulmonary hypertension (PH) which could affect management of COVID-19. This should be considered in those who are acutely ill as patients can develop increased pulmonary pressures and, at times, right sided heart failure during ACS (particularly in those with known PH) and if these are present, consultation with Cardiology or Pulmonary is warranted.<\/li>\n<li>Significant numbers of patients with SCD have co-morbid asthma which may be exacerbated by acute viral illnesses. Review your hospital policies regarding the use of nebulizers during the COVID-19 pandemic as many institutions have advised against the use of aerosol-based interventions. Under such circumstances, consider using metered-dose inhaler instead.<\/li>\n<li>Many SCD patients are chronically prescribed NSAIDs, angiotensin converting enzyme inhibitors, and angiotensin II receptor blockers. Data are emerging regarding possible negative effects of these classes of drugs on people being treated for COVID-19. We suggest regular review of emerging data to guide decision-making about these drugs on a case-by-case basis.<\/li>\n<li><strong>Management of hypercoagulability:<\/strong><\/li>\n<li>COVID is associated with elevated D-dimer, prolongation of the prothrombin time, thrombocytopenia, reduction fibrinogen and these have prognostic significance in infected individuals without sickle cell disease. Such findings are also common in sickle cell patients with severe acute chest and multiorgan failure. These should be measured and monitored in all patients admitted with COVID infection and a risk stratification algorithm has been developed by the International Society of Thrombosis and Hemostasis. <a href=\"blank\">https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1111\/jth.14810<\/a>. Also see ASH recommendations. <a href=\"blank\">https:\/\/hematology.org\/covid-19\/covid-19-and-coagulopathy<\/a>.<\/li>\n<li>There also appears to be an increased risk of thrombosis with or without SCD. ISTH also recommends that prophylactic heparin be considered in all hospitalized patients that are not bleeding and who have platelet counts greater than 25,000. Anticoagulation and risk stratification recommendations for children and adults hospitalized with COVID are available from the American Society of Hematology <a href=\"blank\">https:\/\/hematology.org\/covid-19\/covid-19-and-vte-anticoagulation<\/a>\n<ul>\n<li><strong>Kawasaki-like syndrome.<\/strong><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<ul>\n<li>Recent reports highlight an\u00a0increase\u00a0in children of a Kawasaki\u2013like disease, a systemic vasculitis, sometimes presenting in a very severe form. While the connection with COVID-19 has yet to be demonstrated, these data should be taken into careful consideration in the upcoming months. (See \u00a0 <a href=\"blank\">https:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140-6736(20)31103-X\/fulltext<\/a>)<\/li>\n<\/ul>\n<ul>\n<li><strong>Managing the COVID-19+ SCD patient following discharge from the hospital.<\/strong><\/li>\n<\/ul>\n<ul>\n<li>Patients with SCD who are discharged from the hospital and known to be COVID-19 positive remain at risk for serious complications including the acute chest syndrome and secondary bacterial infection.<\/li>\n<li>Patients should only be discharged if close outpatient follow up can be instituted, preferably with daily phone calls to the patient by an outpatient provider (physician or nurse) to assess for symptoms suggesting progression of COVID-19 disease severity or the development of sickle cell-related complications.<\/li>\n<\/ul>\n<p>In the setting of blood shortage, clinicians will need to prioritize transfusions according to clinical need. Highest priority indications for continued transfusion include stroke prevention, progressive or critical neurovascular disease, those with recurrent acute chest syndrome unresponsive to Hydroxyurea, and significant cardiac or respiratory co-morbidity. To date, data suggest that transfusions remain safe.<\/p>\n<ul>\n<li>Monitor the availability of blood in your community closely as you may have to adjust your transfusion practices (e.g. apheresis vs manual\/simple transfusion) to maintain current individual patient treatment goals.<\/li>\n<li>Consider transitioning to Hydroxyurea for patients eligible according to TWITCH (Ware et al Lancet 2016).<\/li>\n<li>If you match for CEK antigens, please continue.<\/li>\n<li>Indications where maintenance of current transfusion strategy is imperative:<\/li>\n<li>Children with history of stroke\/abnormal TCD: maintain HbS &lt; 30% or continue current strategy*.<\/li>\n<li>Adults with history of stroke or abnormal TCD as children: maintain HbS &lt; 30% or continue current strategy*.<\/li>\n<li>Consider modification of transfusion strategy in order to conserve blood in the following:<\/li>\n<li>Patients receiving chronic transfusion for recurrent acute chest syndrome: continue current strategy*, individualize for maintenance of HbS &lt; 30% vs &lt; 50%, consider adding disease-modifying drug (Hydroxyurea).<\/li>\n<li>Patients on RBC exchange for end organ damage, priapism, or other non-neurologic indication: switch to simple transfusion or partial exchange for 3-6 months or until blood supply recovers, if baseline hematocrit allows (individualize, generally maintain hematocrit &lt;33%).<\/li>\n<\/ul>\n<p><em>*for patients who may be stable with a HbS goal that is <u>&gt;<\/u> 30%, maintain current goal<\/em><\/p>\n<ul>\n<li><strong>Encourage people to Donate, Donate, Donate.<\/strong>\n<ul>\n<li>Medical leaders should encourage local communities and political leadership to support local blood drives as blood shortages are<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<ul>\n<li>During \u201cshelter in place\u201d, blood donation probably is considered an essential activity.<\/li>\n<li>We are not aware of any clinical trials in COVID-19 specifically for SCD. However, a non-research global registry collecting only de-identified data has been established as a voluntary effort to identify the impact of COVID-19 on people with SCD: https:\/\/covidsicklecell.org\/<\/li>\n<li>People with SCD should not be excluded <em>a priori<\/em> from COVID-19 clinical trials.<\/li>\n<li>Modify other ongoing clinical trials for the safety of patients and staff.<\/li>\n<li>Halt all other new research enrollment requiring a patient visit, including gene therapy\/bone marrow transplantation, unless it is deemed in the patient\u2019s best interest or involves COVID-19 clinical investigation or compassionate use protocols for very ill patients.<\/li>\n<\/ul>\n<p>&nbsp;<br \/>\n<strong>Frequently Asked Questions<\/strong><br \/>\n<strong>What should I do if a patient or a parent asks for a letter for work?<\/strong><\/p>\n<ul>\n<li>Prepare a form letter that supports their request to work at home and can be easily customized for each patient. Highlight that SCD is considered to be a high-risk condition for severe COVID-19 infection. <a href=\"blank\">sicklecelldisease.org\/template-letters-for-caregivers-2\/<\/a><\/li>\n<\/ul>\n<p><strong>How can I get information for my patients about COVID-19?<\/strong><\/p>\n<ul>\n<li>Please have them go to <a href=\"blank\">sicklecelldisease.org<\/a> where they can get updated information that is specific for patients and their caregivers.<\/li>\n<\/ul>\n<h3><strong>SCDAA Medical and Research Advisory Committee Members<\/strong><\/h3>\n<p><span style=\"color: #ff0000\">Miguel R Abboud, MD<\/span><br \/>\nProfessor of Pediatrics and Pediatric Hematology-Oncology<br \/>\nChairman<br \/>\nDepartment of Pediatrics and Adolescent Medicine<br \/>\nAmerican University of Beirut<br \/>\nBeirut, Lebanon<br \/>\n<span style=\"color: #ff0000\">Biree Andemariam, MD<\/span><br \/>\nChair, Medical and Research Advisory Committee, Sickle Cell Disease Association of America<br \/>\nChief Medical Officer, Sickle Cell Disease Association of America<br \/>\nDirector, New England Sickle Cell Institute Associate Professor of Medicine<br \/>\nUniversity of Connecticut Health<br \/>\nFarmington, Connecticut<br \/>\n<span style=\"color: #ff0000\">Shawn Bediako, PhD Associate Professor Department of Psychology<\/span><br \/>\nUniversity of Maryland Baltimore County Baltimore, Maryland<br \/>\nAndrew Campbell, MD<br \/>\nCenter for Cancer and Blood Disorders Children&#8217;s National Health System Associate Professor of Pediatrics<br \/>\nGeorge Washington University School of Medicine and Health Sciences<br \/>\nWashington, District of Columbia<br \/>\n<span style=\"color: #ff0000\">Raffaella Colombatti, MD, PhD<\/span><br \/>\nPhysician Azienda Ospedaliera-Universit\u00e0 di Padova<br \/>\nDepartment of Womens&#8217; and Child Health Clinic of Pediatric Hematology Oncology Via Giustiniani 3<br \/>\n35129 Padova, Italy<br \/>\n<span style=\"color: #ff0000\">Lori Crosby, PsyD<\/span><br \/>\nCo-Director, Innovations in Community Research, Division of Behavioral Medicine &amp; Clinical Psychology<br \/>\nCo-Director, CCTST, Community Engagement Core<br \/>\nPsychologist, Research, Behavioral Medicine<br \/>\n&amp; Clinical Psychologist<br \/>\nCincinnati Children\u2019s<br \/>\nProfessor, UC Department of Pediatrics<br \/>\nCincinnati, OH<br \/>\n<span style=\"color: #ff0000\">Deepika Darbari, MD<\/span><br \/>\nCenter for Cancer and Blood Disorders Children&#8217;s National Health System Associate Professor of Pediatrics<br \/>\nGeorge Washington University School of Medicine and Health Sciences<br \/>\nWashington, DC<br \/>\n<span style=\"color: #ff0000\">Payal Desai, MD Associate Professor<\/span><br \/>\nDirector of Sickle Cell Research<br \/>\nThe Ohio State University<br \/>\nJamesCare at Ohio State East Hospital<br \/>\nColumbus, Ohio<br \/>\n<span style=\"color: #ff0000\">James Eckman, MD<\/span><br \/>\nProfessor Emeritus, Hematology &amp; Medical Oncology<br \/>\nEmory University School of Medicine Department of Hematology and Medical Oncology<br \/>\nAtlanta, Georgia<br \/>\n<span style=\"color: #ff0000\">Mark Gladwin, MD Professor and Chair Department of Medicine<\/span><br \/>\nFounder, Pittsburgh Heart, Lung, and Blood Vascular Medicine Institute<br \/>\nUniversity of Pittsburgh E1240 BST<br \/>\nPittsburgh, Pennsylvania<br \/>\n<span style=\"color: #ff0000\">Jo Howard, MB Bchir, MRCP, FRCPath<\/span><br \/>\nHead of Red Cell\/Sickle Cell Service Guy&#8217;s and St Thomas&#8217;<br \/>\nNHS Foundation Trust Great Maze Pond<br \/>\nLondon, United Kingdom<br \/>\n<span style=\"color: #ff0000\">Lewis Hsu, MD, PhD<\/span><br \/>\nCo-Chair, Medical and Research Advisory Committee, Sickle Cell Disease Association of America<br \/>\nVice Chief Medical Officer, Sickle Cell Disease Association of America<br \/>\nDirector of Pediatric Sickle Cell<br \/>\nProfessor of Pediatric Hematology- Oncology<br \/>\nUniversity of Illinois at Chicago Chicago, Illinois<br \/>\n<span style=\"color: #ff0000\">Professor Baba Inusa<\/span><br \/>\nLead Consultant Paediatric Sickle Cell and Thalassaemia<br \/>\nEvelina London Children\u2019s Hospital<br \/>\nGuy\u2019s and St Thomas NHS Trust<br \/>\nWomen and Children\u2019s Health<br \/>\nFaculty of Life Sciences &amp; Medicine<br \/>\nKing\u2019s College London<br \/>\nLambeth Palace Road, London SE1 7EH<br \/>\n<span style=\"color: #ff0000\">Elizabeth S. Klings, MD<\/span><br \/>\nAssociate Professor of Medicine<br \/>\nDirector, Center for Excellence in Sickle Cell Disease<br \/>\nDirector, Pulmonary Hypertension Center<br \/>\nBoston University School of Medicine<br \/>\nBoston, Massachusetts<br \/>\n<span style=\"color: #ff0000\">Lakshmanan Krishnamurti, MD Professor of Pediatrics<\/span><br \/>\nDirector of Bone Marrow Transplant<br \/>\nJoseph Kuechenmeister Aflac Field Force Chair, Aflac Cancer and Blood Disorders Center Children\u2019s Healthcare of Atlanta\/Emory University<br \/>\nAtlanta, Georgia<br \/>\n<span style=\"color: #ff0000\">Sophie Lanzkron, MD, MHS<\/span><br \/>\nDirector, Sickle Cell Center for Adults The Johns Hopkins Hospital<br \/>\nBaltimore, Maryland<br \/>\n<span style=\"color: #ff0000\">Julie Makani, FRCP, PhD<\/span><br \/>\nAssociate Professor<br \/>\nDepartment of Haematology and Blood Transfusion<br \/>\nMuhimbili University of Health and Allied Sciences<br \/>\nDar es Salaam, Tanzania<br \/>\n<span style=\"color: #ff0000\">Caterina Minniti, MD Director, Sickle Cell Center Montefiore Health System<\/span><br \/>\nProfessor of Medicine and Pediatrics Albert Einstein College of Medicine<br \/>\nBronx, New York<br \/>\n<span style=\"color: #ff0000\">Genice T. Nelson, DNP, APRN, ANP-BC Program Director<\/span><br \/>\nNew England Sickle Cell Institute &amp; Connecticut Bleeding Disorders Programs UConn Health<br \/>\nFarmington, Connecticut<br \/>\nBoard Member, Sickle Cell Disease Association of America<br \/>\n<span style=\"color: #ff0000\">Isaac Odame, MB ChB, MRCP(UK), FRCPath, FRCPCH, FRCPC<\/span><br \/>\nProfessor, Department of Paediatrics University of Toronto<br \/>\nThe Hospital for Sick Children Division of Haematology\/Oncology<br \/>\nToronto, Ontario<br \/>\n<span style=\"color: #ff0000\">Kwaku Ohene-Frempong, MD<\/span><br \/>\nDirector Emeritus, Comprehensive Sickle Cell Center<br \/>\nEmeritus Professor of Pediatrics, University of Pennsylvania<br \/>\nPresident, Sickle Cell Foundation of Ghana<br \/>\nEmeritus Board Member, Sickle Cell Disease Association of America<br \/>\n<span style=\"color: #ff0000\">Gwendolyn Poles, D.O. Honorary Medical Staff Member<\/span><br \/>\nFormer Medical Director, Kline Health Center<br \/>\nFaculty, Internal Medicine Program UPMC Pinnacle<br \/>\nHarrisburg, Pennsylvania<br \/>\nBoard Member, Sickle Cell Disease Association of America<br \/>\n<span style=\"color: #ff0000\">John Roberts, MD<\/span><br \/>\nYale Adult Sickle Cell Program<br \/>\nSmilow Cancer Hospital at Yale New Haven<br \/>\nNew Haven, Connecticut<br \/>\n<span style=\"color: #ff0000\">Wally Smith, MD<\/span><br \/>\nProfessor<br \/>\nScientific Director, VCU Center on Health Disparities<br \/>\nDirector, VCU Adult Sickle Cell Program Department of Internal Medicine<br \/>\nDivision of General Internal Medicine<br \/>\nRichmond, Virginia<br \/>\n<span style=\"color: #ff0000\">Crawford J. Strunk, MD<\/span><br \/>\nDirector, Sickle Cell Disease and Hemoglobinopathy Clinic<br \/>\nPediatric Hematology\/Oncology<br \/>\nDebbie Brass Cancer Center<br \/>\nProMedica Russell J. Ebeid Children\u2019s Hospital<br \/>\n2142 North Cove Blvd, Ren 4 West<br \/>\nToledo, OH 43606<br \/>\n<span style=\"color: #ff0000\">Immacolata Tartaglione, MD PhD<\/span><br \/>\nDepartment of Woman, Child and General and Specialist Surgery<br \/>\nUniversit\u00e0 degli Studi della Campania \u201cLuigi Vanvitelli\u201d<br \/>\nNaples, Italy<br \/>\n<span style=\"color: #ff0000\">Marsha Treadwell, PhD<\/span><br \/>\nDirector, Sickle Cell Care Coordination Initiative<br \/>\nRegional Director, Pacific Sickle Cell Regional Collaborative<br \/>\nProfessor of Psychiatry and Pediatrics<br \/>\nUniversity of California San Francisco Benioff Children\u2019s Hospital Oakland<br \/>\nOakland, California<br \/>\n<span style=\"color: #ff0000\">Winfred C. Wang, MD<\/span><br \/>\nEmeritus, St. Jude Faculty<br \/>\nMember, Department of Hematology<br \/>\nSt. Jude Children\u2019s Research Hospital<br \/>\nMemphis, Tennessee<br \/>\n<span style=\"color: #ff0000\">Russell E. Ware, MD, PhD<\/span><br \/>\nDirector, Division of Hematology<br \/>\nInstitute Co-Director, Cancer and Blood Diseases Institute<br \/>\nDirector, Global Health Center<br \/>\nMarjory J. Johnson Chair of Hematology Translational Research<br \/>\nCincinnati Children\u2019s<br \/>\nProfessor, UC Department of Pediatrics<br \/>\nCincinnati, Ohio<br \/>\n<span style=\"color: #ff0000\">Julie Kanter Washko, MD<\/span><br \/>\nAssociate Professor<br \/>\nDivision of Hematology Oncology<br \/>\nUniversity of Alabama at Birmingham<br \/>\nBirmingham, Alabama<br \/>\n<span style=\"color: #ff0000\">Kim Smith-Whitley, MD<\/span><br \/>\nProfessor of Pediatrics<br \/>\nDirector Comprehensive Sickle Cell Center Division of Hematology<br \/>\nThe Children&#8217;s Hospital of Philadelphia<br \/>\nPhiladelphia, Pennsylvania<br \/>\nBoard Member, Sickle Cell Disease Association of America<br \/>\n<span style=\"color: #ff0000\">Wanda Whitten-Shurney, MD<\/span><br \/>\nCEO &amp; Medical Director<br \/>\nSickle Cell Disease Association, Michigan Chapter Inc.<br \/>\nBoard Member, Sickle Cell Disease Association of America<br \/>\nDetroit, Michigan<br \/>\n<span style=\"color: #ff0000\">Ahmar U. Zaidi, MD<\/span><br \/>\nAssistant Professor of Pediatrics Comprehensive Sickle Cell Center Children&#8217;s Hospital of Michigan Director of Physician Network Development, University Pediatricians<br \/>\nWayne State University\/Central Michigan University School of Medicine<br \/>\nDetroit, Michigan<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Download Provider Advisory Download Sub-Saharan African Provider Advisory An Outline to Decrease Burden and Minimize Morbidity This document will be updated as data and evidence emerge. May 27, 2020 &#8211; Sickle cell disease (SCD) affects 100,000 individuals in the United States and millions globally. Individuals living with SCD suffer from both acute and chronic complications [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":4001,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[],"class_list":["post-3999","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>NEW - Sickle Cell Disease and COVID-19: Provider Advisory - Sickle Cell Disease Association of America Inc.<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.sicklecelldisease.org\/2020\/03\/18\/sickle-cell-disease-and-covid-19-provider-directory\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"NEW - Sickle Cell Disease and COVID-19: Provider Advisory - Sickle Cell Disease Association of America Inc.\" \/>\n<meta property=\"og:description\" content=\"Download Provider Advisory Download Sub-Saharan African Provider Advisory An Outline to Decrease Burden and Minimize Morbidity This document will be updated as data and evidence emerge. May 27, 2020 &#8211; Sickle cell disease (SCD) affects 100,000 individuals in the United States and millions globally. 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